@article{26a383c312e442299dc1206c44182ec8,
title = "Glycosyloxyamine neoglycosylation: A model study using calicheamicin",
abstract = "Sweetness \& light! The glycosyloxyamine glycoside of calicheamicin was exploited to form neo-D-ribosides in one efficient chemoselective step. Assessment of the neoglycosides revealed only slight reductions in cytotoxicity or ability to cleave DNA compared to the parent aglycons. This study exposes a previously unrecognized method for efficient calicheamicin bioconjugation amenable to a wide range of cancer- selective targeting modalities.",
keywords = "Carbohydrates, Enediynes, Glycosides, Glycosylation, Natural products",
author = "Goff, \{Randal D.\} and Shanteri Singh and Thorson, \{Jon S.\}",
year = "2011",
month = may,
day = "2",
doi = "10.1002/cmdc.201100028",
language = "English",
volume = "6",
pages = "774--776",
number = "5",
}
