Hepatic hemangioma in cirrhotics with portal hypertension: Evaluation with Tc-99m red blood cell SPECT

Dwight M. Achong; Elizabeth Oates

doi:10.1148/radiology.191.1.8134555

Hepatic hemangioma in cirrhotics with portal hypertension: Evaluation with Tc-99m red blood cell SPECT

Dwight M. Achong, Elizabeth Oates

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

PURPOSE: To determine whether extensive shunting associated with portal hypertension (PH) adversely affects the diagnostic accuracy of technetium- 99m red blood cell (RBC) single photon emission computed tomography (SPECT) for hepatic hemangioma (HH). MATERIALS AND METHODS: Nineteen possible HHs (1.0-11.0 cm in diameter) in 15 cirrhotics with PH were studied with RBC SPECT. RESULTS: RBC SPECT allowed correct categorization of four HHs (1.5, 2.8, 4.0, and 4.0 cm in diameter) and 13 non-HHs (1.5-11.0 cm in diameter). Two small HHs (1.0 and 1.4 cm in diameter) were 'missed.' Sensitivity, specificity, and accuracy were 67%, 100%, and 89%, respectively. CONCLUSION: Despite abnormal liver blood flow dynamics due to portosystemic collateralization, RBC SPECT allows reliable identification of HH in cirrhotics with PH. As in noncirrhotics, its major limitation is small lesion size.

Original language	English
Pages (from-to)	115-117
Number of pages	3
Journal	Radiology
Volume	191
Issue number	1
DOIs	https://doi.org/10.1148/radiology.191.1.8134555
State	Published - Apr 1994

Keywords

Angioma, gastrointestinal tract
Emission CT (ECT)
Hypertension, portal
Liver neoplasms, radionuclide studies
Liver, cirrhosis

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1148/radiology.191.1.8134555

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@article{086089f350224cc9880bf8d5e3a5e8d8,

title = "Hepatic hemangioma in cirrhotics with portal hypertension: Evaluation with Tc-99m red blood cell SPECT",

abstract = "PURPOSE: To determine whether extensive shunting associated with portal hypertension (PH) adversely affects the diagnostic accuracy of technetium- 99m red blood cell (RBC) single photon emission computed tomography (SPECT) for hepatic hemangioma (HH). MATERIALS AND METHODS: Nineteen possible HHs (1.0-11.0 cm in diameter) in 15 cirrhotics with PH were studied with RBC SPECT. RESULTS: RBC SPECT allowed correct categorization of four HHs (1.5, 2.8, 4.0, and 4.0 cm in diameter) and 13 non-HHs (1.5-11.0 cm in diameter). Two small HHs (1.0 and 1.4 cm in diameter) were 'missed.' Sensitivity, specificity, and accuracy were 67%, 100%, and 89%, respectively. CONCLUSION: Despite abnormal liver blood flow dynamics due to portosystemic collateralization, RBC SPECT allows reliable identification of HH in cirrhotics with PH. As in noncirrhotics, its major limitation is small lesion size.",

keywords = "Angioma, gastrointestinal tract, Emission CT (ECT), Hypertension, portal, Liver neoplasms, radionuclide studies, Liver, cirrhosis",

author = "Achong, {Dwight M.} and Elizabeth Oates",

year = "1994",

month = apr,

doi = "10.1148/radiology.191.1.8134555",

language = "English",

volume = "191",

pages = "115--117",

number = "1",

}

TY - JOUR

T1 - Hepatic hemangioma in cirrhotics with portal hypertension

T2 - Evaluation with Tc-99m red blood cell SPECT

AU - Achong, Dwight M.

AU - Oates, Elizabeth

PY - 1994/4

Y1 - 1994/4

N2 - PURPOSE: To determine whether extensive shunting associated with portal hypertension (PH) adversely affects the diagnostic accuracy of technetium- 99m red blood cell (RBC) single photon emission computed tomography (SPECT) for hepatic hemangioma (HH). MATERIALS AND METHODS: Nineteen possible HHs (1.0-11.0 cm in diameter) in 15 cirrhotics with PH were studied with RBC SPECT. RESULTS: RBC SPECT allowed correct categorization of four HHs (1.5, 2.8, 4.0, and 4.0 cm in diameter) and 13 non-HHs (1.5-11.0 cm in diameter). Two small HHs (1.0 and 1.4 cm in diameter) were 'missed.' Sensitivity, specificity, and accuracy were 67%, 100%, and 89%, respectively. CONCLUSION: Despite abnormal liver blood flow dynamics due to portosystemic collateralization, RBC SPECT allows reliable identification of HH in cirrhotics with PH. As in noncirrhotics, its major limitation is small lesion size.

AB - PURPOSE: To determine whether extensive shunting associated with portal hypertension (PH) adversely affects the diagnostic accuracy of technetium- 99m red blood cell (RBC) single photon emission computed tomography (SPECT) for hepatic hemangioma (HH). MATERIALS AND METHODS: Nineteen possible HHs (1.0-11.0 cm in diameter) in 15 cirrhotics with PH were studied with RBC SPECT. RESULTS: RBC SPECT allowed correct categorization of four HHs (1.5, 2.8, 4.0, and 4.0 cm in diameter) and 13 non-HHs (1.5-11.0 cm in diameter). Two small HHs (1.0 and 1.4 cm in diameter) were 'missed.' Sensitivity, specificity, and accuracy were 67%, 100%, and 89%, respectively. CONCLUSION: Despite abnormal liver blood flow dynamics due to portosystemic collateralization, RBC SPECT allows reliable identification of HH in cirrhotics with PH. As in noncirrhotics, its major limitation is small lesion size.

KW - Angioma, gastrointestinal tract

KW - Emission CT (ECT)

KW - Hypertension, portal

KW - Liver neoplasms, radionuclide studies

KW - Liver, cirrhosis

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SN - 0033-8419

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JO - Radiology

JF - Radiology

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Hepatic hemangioma in cirrhotics with portal hypertension: Evaluation with Tc-99m red blood cell SPECT

Abstract

Keywords

ASJC Scopus subject areas

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