High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes

Zyad T. Saleh; Terry A. Lennie; Abdullah S. Alhurani; Issa M. Almansour; Hamza Alduraidi; Debra K. Moser

doi:10.1177/1054773819888743

High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes

Zyad T. Saleh, Terry A. Lennie, Abdullah S. Alhurani, Issa M. Almansour, Hamza Alduraidi, Debra K. Moser

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The aim was to determine whether 24-hour urine sodium excretion predicted event-free survival of patients with heart failure (HF) and diabetes mellitus (DM). Twenty-four hour urine sodium, as an indicator of dietary sodium, was collected from 107 patients with HF and comorbid DM. Patients were followed for a median period of 337 days to determine time to the first event of either all-cause hospitalization or cardiac-related mortality. There were 44 patients (41%) who had an event of death or hospitalization. Cox regression showed that higher urine sodium (>3.8 gm/day) was associated with 2.8 times greater risk for an event than lower urine sodium after controlling for age, gender, New York Heart Association class (I/II vs. III/IV), left ventricular ejection fraction, and body mass index. These data suggest that dietary sodium restriction may be beneficial for patients with HF and DM.

Original language	English
Pages (from-to)	154-160
Number of pages	7
Journal	Clinical Nursing Research
Volume	30
Issue number	2
DOIs	https://doi.org/10.1177/1054773819888743
State	Published - Feb 2021

Bibliographical note

Funding Information:
https://orcid.org/0000-0002-1107-0413 Saleh Zyad T. PhD, RN 1 Lennie Terry A. PhD, RN, FAAN 2 Alhurani Abdullah S. PhD, MSN, MBA, RN 1 Almansour Issa M. PhD, MPhil, RN 1 https://orcid.org/0000-0003-1762-0575 Alduraidi Hamza PhD, MPH, RN 1 Moser Debra K. PhD, RN, FAAN 2 1 School of Nursing, The University of Jordan, Amman, Jordan 2 College of Nursing, University of Kentucky, Lexington, KY, USA Zyad T. Saleh, PhD, RN, Department of Clinical Nursing, School of Nursing, The University of Jordan, Amman, 11942, Jordan. Email: zyad.saleh2@ju.edu.jo 11 2019 1054773819888743 © The Author(s) 2019 2019 SAGE Publications The aim was to determine whether 24-hour urine sodium excretion predicted event-free survival of patients with heart failure (HF) and diabetes mellitus (DM). Twenty-four hour urine sodium, as an indicator of dietary sodium, was collected from 107 patients with HF and comorbid DM. Patients were followed for a median period of 337 days to determine time to the first event of either all-cause hospitalization or cardiac-related mortality. There were 44 patients (41%) who had an event of death or hospitalization. Cox regression showed that higher urine sodium (>3.8 gm/day) was associated with 2.8 times greater risk for an event than lower urine sodium after controlling for age, gender, New York Heart Association class (I/II vs. III/IV), left ventricular ejection fraction, and body mass index. These data suggest that dietary sodium restriction may be beneficial for patients with HF and DM. heart failure diabetes mellitus dietary sodium intake health outcome indiana university https://doi.org/10.13039/100006733 M01RR000750 National Center for Advancing Translational Sciences https://doi.org/10.13039/100006108 NIH UL1TR000117 national center for research resources https://doi.org/10.13039/100000097 NIH UL1 RR025008 national institute of nursing research https://doi.org/10.13039/100000056 national institute of nursing research https://doi.org/10.13039/100000056 P20NR0106791 national institute of nursing research https://doi.org/10.13039/100000056 RO1NR009280 edited-state corrected-proof Declaration of Conflicting Interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by National Institute of Nursing Research NIH RO1NR009280, National Institute of Nursing Research NIH P20NR0106791, American Heart Association, Great Rivers Affiliate Postdoctoral Fellowship, National Center for Research Resources, NIH UL1 RR025008, National Center for Advancing Translational Sciences, NIH UL1TR000117, General Clinical Research Centers NIH: Indiana University M01RR000750, Atlanta Veterans Administration Medical Center, and Clarian Health Partners (Indiana). ORCID iDs Zyad T. Saleh https://orcid.org/0000-0002-1107-0413 Hamza Alduraidi https://orcid.org/0000-0003-1762-0575

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by National Institute of Nursing Research NIH RO1NR009280, National Institute of Nursing Research NIH P20NR0106791, American Heart Association, Great Rivers Affiliate Postdoctoral Fellowship, National Center for Research Resources, NIH UL1 RR025008, National Center for Advancing Translational Sciences, NIH UL1TR000117, General Clinical Research Centers NIH: Indiana University M01RR000750, Atlanta Veterans Administration Medical Center, and Clarian Health Partners (Indiana).

Publisher Copyright:
© The Author(s) 2019.

Keywords

diabetes mellitus
dietary sodium intake
health outcome
heart failure

ASJC Scopus subject areas

Nursing (all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/1054773819888743

Cite this

@article{82ec91360cf947dd8134d3add52a3914,

title = "High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes",

abstract = "The aim was to determine whether 24-hour urine sodium excretion predicted event-free survival of patients with heart failure (HF) and diabetes mellitus (DM). Twenty-four hour urine sodium, as an indicator of dietary sodium, was collected from 107 patients with HF and comorbid DM. Patients were followed for a median period of 337 days to determine time to the first event of either all-cause hospitalization or cardiac-related mortality. There were 44 patients (41%) who had an event of death or hospitalization. Cox regression showed that higher urine sodium (>3.8 gm/day) was associated with 2.8 times greater risk for an event than lower urine sodium after controlling for age, gender, New York Heart Association class (I/II vs. III/IV), left ventricular ejection fraction, and body mass index. These data suggest that dietary sodium restriction may be beneficial for patients with HF and DM.",

keywords = "diabetes mellitus, dietary sodium intake, health outcome, heart failure",

author = "Saleh, {Zyad T.} and Lennie, {Terry A.} and Alhurani, {Abdullah S.} and Almansour, {Issa M.} and Hamza Alduraidi and Moser, {Debra K.}",

note = "Funding Information: https://orcid.org/0000-0002-1107-0413 Saleh Zyad T. PhD, RN 1 Lennie Terry A. PhD, RN, FAAN 2 Alhurani Abdullah S. PhD, MSN, MBA, RN 1 Almansour Issa M. PhD, MPhil, RN 1 https://orcid.org/0000-0003-1762-0575 Alduraidi Hamza PhD, MPH, RN 1 Moser Debra K. PhD, RN, FAAN 2 1 School of Nursing, The University of Jordan, Amman, Jordan 2 College of Nursing, University of Kentucky, Lexington, KY, USA Zyad T. Saleh, PhD, RN, Department of Clinical Nursing, School of Nursing, The University of Jordan, Amman, 11942, Jordan. Email: zyad.saleh2@ju.edu.jo 11 2019 1054773819888743 {\textcopyright} The Author(s) 2019 2019 SAGE Publications The aim was to determine whether 24-hour urine sodium excretion predicted event-free survival of patients with heart failure (HF) and diabetes mellitus (DM). Twenty-four hour urine sodium, as an indicator of dietary sodium, was collected from 107 patients with HF and comorbid DM. Patients were followed for a median period of 337 days to determine time to the first event of either all-cause hospitalization or cardiac-related mortality. There were 44 patients (41%) who had an event of death or hospitalization. Cox regression showed that higher urine sodium (>3.8 gm/day) was associated with 2.8 times greater risk for an event than lower urine sodium after controlling for age, gender, New York Heart Association class (I/II vs. III/IV), left ventricular ejection fraction, and body mass index. These data suggest that dietary sodium restriction may be beneficial for patients with HF and DM. heart failure diabetes mellitus dietary sodium intake health outcome indiana university https://doi.org/10.13039/100006733 M01RR000750 National Center for Advancing Translational Sciences https://doi.org/10.13039/100006108 NIH UL1TR000117 national center for research resources https://doi.org/10.13039/100000097 NIH UL1 RR025008 national institute of nursing research https://doi.org/10.13039/100000056 national institute of nursing research https://doi.org/10.13039/100000056 P20NR0106791 national institute of nursing research https://doi.org/10.13039/100000056 RO1NR009280 edited-state corrected-proof Declaration of Conflicting Interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by National Institute of Nursing Research NIH RO1NR009280, National Institute of Nursing Research NIH P20NR0106791, American Heart Association, Great Rivers Affiliate Postdoctoral Fellowship, National Center for Research Resources, NIH UL1 RR025008, National Center for Advancing Translational Sciences, NIH UL1TR000117, General Clinical Research Centers NIH: Indiana University M01RR000750, Atlanta Veterans Administration Medical Center, and Clarian Health Partners (Indiana). ORCID iDs Zyad T. Saleh https://orcid.org/0000-0002-1107-0413 Hamza Alduraidi https://orcid.org/0000-0003-1762-0575 Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by National Institute of Nursing Research NIH RO1NR009280, National Institute of Nursing Research NIH P20NR0106791, American Heart Association, Great Rivers Affiliate Postdoctoral Fellowship, National Center for Research Resources, NIH UL1 RR025008, National Center for Advancing Translational Sciences, NIH UL1TR000117, General Clinical Research Centers NIH: Indiana University M01RR000750, Atlanta Veterans Administration Medical Center, and Clarian Health Partners (Indiana). Publisher Copyright: {\textcopyright} The Author(s) 2019.",

year = "2021",

month = feb,

doi = "10.1177/1054773819888743",

language = "English",

volume = "30",

pages = "154--160",

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T1 - High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes

AU - Saleh, Zyad T.

AU - Lennie, Terry A.

AU - Alhurani, Abdullah S.

AU - Almansour, Issa M.

AU - Alduraidi, Hamza

AU - Moser, Debra K.

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High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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