High Dietary Sodium Intake is Associated with Shorter Event-Free Survival in Patients with Heart Failure and Comorbid Diabetes

Zyad T. Saleh, Terry A. Lennie, Abdullah S. Alhurani, Issa M. Almansour, Hamza Alduraidi, Debra K. Moser

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The aim was to determine whether 24-hour urine sodium excretion predicted event-free survival of patients with heart failure (HF) and diabetes mellitus (DM). Twenty-four hour urine sodium, as an indicator of dietary sodium, was collected from 107 patients with HF and comorbid DM. Patients were followed for a median period of 337 days to determine time to the first event of either all-cause hospitalization or cardiac-related mortality. There were 44 patients (41%) who had an event of death or hospitalization. Cox regression showed that higher urine sodium (>3.8 gm/day) was associated with 2.8 times greater risk for an event than lower urine sodium after controlling for age, gender, New York Heart Association class (I/II vs. III/IV), left ventricular ejection fraction, and body mass index. These data suggest that dietary sodium restriction may be beneficial for patients with HF and DM.

Original languageEnglish
Pages (from-to)154-160
Number of pages7
JournalClinical Nursing Research
Volume30
Issue number2
DOIs
StatePublished - Feb 2021

Bibliographical note

Publisher Copyright:
© The Author(s) 2019.

Keywords

  • diabetes mellitus
  • dietary sodium intake
  • health outcome
  • heart failure

ASJC Scopus subject areas

  • General Nursing

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