High-precision microcontact printing of interchangeable stamps using an integrated kinematic coupling

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Microcontact printing (CP) is a rapid, inexpensive way to create microscale chemical or biochemical patterns on a target surface. This microstamping method can be used to selectively modify a wide array of surface properties, from wettability and protein adsorption to chemical etch susceptibility. However, controlling the absolute location of features created with microcontact printing is difficult; this lack of precision makes it challenging to integrate with other microfabrication methods or to create complex, multi-chemical patterns on a single surface. In this research, we demonstrate a novel method of controlling the placement of microcontact printing stamps by using an integrated kinematic coupling device. This technique relies on mechanical reference points for rapid, optics-free registry of the stamp and allows CP stamps to be quickly removed and replaced or even exchanged with submicron repeatability.

Original languageEnglish
Pages (from-to)455-459
Number of pages5
JournalLab on a Chip
Issue number3
StatePublished - Feb 7 2011

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • General Chemistry
  • Biomedical Engineering


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