TY - JOUR
T1 - High prevalence of cholesterol-rich atherosclerotic lesions in ancient mummies
T2 - A near-infrared spectroscopy study
AU - Madjid, Mohammad
AU - Safavi-Naeini, P.
AU - Lodder, Robert
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/10
Y1 - 2019/10
N2 - Computed tomography has been used previously in mummies to detect arterial calcification, which is a marker of later-stage atherosclerosis. Here, using the novel approach of near-infrared spectroscopy, we detected cholesterol-rich atherosclerotic plaques in arterial samples from ancient mummies. In this proof-of-concept study, we are the first to noninvasively detect these earlier-stage lesions in mummies from different geographical areas, suggesting that atherosclerosis has been present in humans since ancient times.
AB - Computed tomography has been used previously in mummies to detect arterial calcification, which is a marker of later-stage atherosclerosis. Here, using the novel approach of near-infrared spectroscopy, we detected cholesterol-rich atherosclerotic plaques in arterial samples from ancient mummies. In this proof-of-concept study, we are the first to noninvasively detect these earlier-stage lesions in mummies from different geographical areas, suggesting that atherosclerosis has been present in humans since ancient times.
UR - http://www.scopus.com/inward/record.url?scp=85070538368&partnerID=8YFLogxK
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U2 - 10.1016/j.ahj.2019.06.018
DO - 10.1016/j.ahj.2019.06.018
M3 - Letter
C2 - 31422195
AN - SCOPUS:85070538368
SN - 0002-8703
VL - 216
SP - 113
EP - 116
JO - American Heart Journal
JF - American Heart Journal
ER -