Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis

R. S. Veazey, H. W. Taylor, D. W. Horohov, J. L. Krahenbuhl, J. L. Oliver, T. G. Snider

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalJournal of Comparative Pathology
Issue number1
StatePublished - Jul 1995

Bibliographical note

Funding Information:
This work was supported in part by a grant from the Louisiana State University School of Veterinary Medicine. We give special thanks to Cheryl Crowder, Mae Lopez, Del Phillips, and Cindy Berry for their excellent technical assistance and support. This manuscript fulfils, in part, the requirements for the degree of Doctor of Philosophy in the Interdepartmental Program in Veterinary Medical Sciences, Department of Veterinary Pathology, Louisiana State University.

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Veterinary (all)


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