Abstract
The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.
Original language | English |
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Pages (from-to) | 75-80 |
Number of pages | 6 |
Journal | Journal of Comparative Pathology |
Volume | 113 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1995 |
Bibliographical note
Funding Information:This work was supported in part by a grant from the Louisiana State University School of Veterinary Medicine. We give special thanks to Cheryl Crowder, Mae Lopez, Del Phillips, and Cindy Berry for their excellent technical assistance and support. This manuscript fulfils, in part, the requirements for the degree of Doctor of Philosophy in the Interdepartmental Program in Veterinary Medical Sciences, Department of Veterinary Pathology, Louisiana State University.
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Veterinary (all)