Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis

R. S. Veazey; H. W. Taylor; D. W. Horohov; J. L. Krahenbuhl; J. L. Oliver; T. G. Snider

doi:10.1016/S0021-9975(05)80071-4

Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis

R. S. Veazey, H. W. Taylor, D. W. Horohov, J. L. Krahenbuhl, J. L. Oliver, T. G. Snider

Veterinary Science

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.

Original language	English
Pages (from-to)	75-80
Number of pages	6
Journal	Journal of Comparative Pathology
Volume	113
Issue number	1
DOIs	https://doi.org/10.1016/S0021-9975(05)80071-4
State	Published - Jul 1995

Bibliographical note

Funding Information:
This work was supported in part by a grant from the Louisiana State University School of Veterinary Medicine. We give special thanks to Cheryl Crowder, Mae Lopez, Del Phillips, and Cindy Berry for their excellent technical assistance and support. This manuscript fulfils, in part, the requirements for the degree of Doctor of Philosophy in the Interdepartmental Program in Veterinary Medical Sciences, Department of Veterinary Pathology, Louisiana State University.

ASJC Scopus subject areas

Pathology and Forensic Medicine
General Veterinary

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10.1016/S0021-9975(05)80071-4

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title = "Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis",

abstract = "The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.",

author = "Veazey, {R. S.} and Taylor, {H. W.} and Horohov, {D. W.} and Krahenbuhl, {J. L.} and Oliver, {J. L.} and Snider, {T. G.}",

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AU - Krahenbuhl, J. L.

AU - Oliver, J. L.

AU - Snider, T. G.

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N2 - The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.

AB - The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.

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Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis

Abstract

Bibliographical note

ASJC Scopus subject areas

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