HIV-1 assembly and budding as targets for drug discovery

Feng Li; Carl Wild

HIV-1 assembly and budding as targets for drug discovery

Feng Li, Carl Wild

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Research conducted during the past several years has led to an increased understanding of the roles played by the viral protein Gag and specific cellular factors in HIV assembly/budding. The identification of compounds that interfere with this process validates this late step in virus replication as a target for HIV therapeutic discovery. In this review, current understanding of HIV-1 assembly/budding is described and several developmental stage drugs that target this process are reviewed.

Original language	English
Pages (from-to)	148-154
Number of pages	7
Journal	Current Opinion in Investigational Drugs
Volume	6
Issue number	2
State	Published - 2005

Keywords

Assembly
Budding
Drug
HIV-1
Target

ASJC Scopus subject areas

Pharmacology
Drug Discovery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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KW - Assembly

KW - Budding

KW - Drug

KW - HIV-1

KW - Target

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M3 - Review article

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AN - SCOPUS:15744370269

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ER -

HIV-1 assembly and budding as targets for drug discovery

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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