HIV-1 assembly and budding as targets for drug discovery

Feng Li; Carl Wild

HIV-1 assembly and budding as targets for drug discovery

Feng Li
, Carl Wild

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Research conducted during the past several years has led to an increased understanding of the roles played by the viral protein Gag and specific cellular factors in HIV assembly/budding. The identification of compounds that interfere with this process validates this late step in virus replication as a target for HIV therapeutic discovery. In this review, current understanding of HIV-1 assembly/budding is described and several developmental stage drugs that target this process are reviewed.

Original language	English
Pages (from-to)	148-154
Number of pages	7
Journal	Current Opinion in Investigational Drugs
Volume	6
Issue number	2
State	Published - 2005

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Assembly
Budding
Drug
HIV-1
Target

ASJC Scopus subject areas

Pharmacology
Drug Discovery

Cite this

@article{055c284c39874ca5b8d46b6216191df7,

title = "HIV-1 assembly and budding as targets for drug discovery",

abstract = "Research conducted during the past several years has led to an increased understanding of the roles played by the viral protein Gag and specific cellular factors in HIV assembly/budding. The identification of compounds that interfere with this process validates this late step in virus replication as a target for HIV therapeutic discovery. In this review, current understanding of HIV-1 assembly/budding is described and several developmental stage drugs that target this process are reviewed.",

keywords = "Assembly, Budding, Drug, HIV-1, Target",

author = "Feng Li and Carl Wild",

year = "2005",

language = "English",

volume = "6",

pages = "148--154",

number = "2",

}

TY - JOUR

T1 - HIV-1 assembly and budding as targets for drug discovery

AU - Li, Feng

AU - Wild, Carl

PY - 2005

Y1 - 2005

N2 - Research conducted during the past several years has led to an increased understanding of the roles played by the viral protein Gag and specific cellular factors in HIV assembly/budding. The identification of compounds that interfere with this process validates this late step in virus replication as a target for HIV therapeutic discovery. In this review, current understanding of HIV-1 assembly/budding is described and several developmental stage drugs that target this process are reviewed.

AB - Research conducted during the past several years has led to an increased understanding of the roles played by the viral protein Gag and specific cellular factors in HIV assembly/budding. The identification of compounds that interfere with this process validates this late step in virus replication as a target for HIV therapeutic discovery. In this review, current understanding of HIV-1 assembly/budding is described and several developmental stage drugs that target this process are reviewed.

KW - Assembly

KW - Budding

KW - Drug

KW - HIV-1

KW - Target

UR - https://www.scopus.com/pages/publications/15744370269

UR - https://www.scopus.com/pages/publications/15744370269#tab=citedBy

M3 - Review article

C2 - 15751737

AN - SCOPUS:15744370269

SN - 1472-4472

VL - 6

SP - 148

EP - 154

JO - Current Opinion in Investigational Drugs

JF - Current Opinion in Investigational Drugs

IS - 2

ER -

HIV-1 assembly and budding as targets for drug discovery

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this