TY - JOUR
T1 - Human breast cancer stem cell markers CD44 and CD24
T2 - Enriching for cells with functional properties in mice or in man?
AU - Fillmore, Christine
AU - Kuperwasser, Charlotte
PY - 2007/5/29
Y1 - 2007/5/29
N2 - Identification of breast cancer stem cells as the cells within breast tumors that have the ability to give rise to cells that make up the bulk of the tumor mass has shifted the focus of cancer research. However, there is still much debate concerning the unique nature of the markers that distinguish cancer stem cells in the breast. As such, understanding whether CD44+/CD24- breast cancer cells are merely more successful in overcoming an engraftment incompatibility that exists when injecting human cells into the mouse adipose tissue or are indeed bona fide cancer stem cells is of great importance.
AB - Identification of breast cancer stem cells as the cells within breast tumors that have the ability to give rise to cells that make up the bulk of the tumor mass has shifted the focus of cancer research. However, there is still much debate concerning the unique nature of the markers that distinguish cancer stem cells in the breast. As such, understanding whether CD44+/CD24- breast cancer cells are merely more successful in overcoming an engraftment incompatibility that exists when injecting human cells into the mouse adipose tissue or are indeed bona fide cancer stem cells is of great importance.
UR - http://www.scopus.com/inward/record.url?scp=34548217968&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548217968&partnerID=8YFLogxK
U2 - 10.1186/bcr1673
DO - 10.1186/bcr1673
M3 - Article
C2 - 17540049
AN - SCOPUS:34548217968
SN - 1465-5411
VL - 9
JO - Breast Cancer Research
JF - Breast Cancer Research
IS - 3
M1 - 303
ER -
