TY - JOUR
T1 - Hydrogels and Hydrogel Nanocomposites
T2 - Enhancing Healthcare through Human and Environmental Treatment
AU - Gutierrez, Angela M.
AU - Frazar, Erin Molly
AU - Maria, Maria Victoria
AU - Paul, Pranto
AU - Hilt, J. Zach
N1 - Publisher Copyright:
© 2021 Wiley-VCH GmbH.
PY - 2022/4/6
Y1 - 2022/4/6
N2 - Humans are constantly exposed to exogenous chemicals throughout their life, which can lead to a multitude of negative health impacts. Advanced materials can play a key role in preventing or mitigating these impacts through a wide variety of applications. The tunable properties of hydrogels and hydrogel nanocomposites (e.g., swelling behavior, biocompatibility, stimuli responsiveness, functionality, etc.) have deemed them ideal platforms for removal of environmental contaminants, detoxification, and reduction of body burden from exogenous chemical exposures for prevention of disease initiation, and advanced treatment of chronic diseases, including cancer, diabetes, and cardiovascular disease. In this review, three main junctures where the use of hydrogel and hydrogel nanocomposite materials can intervene to positively impact human health are highlighted: 1) preventing exposures to environmental contaminants, 2) prophylactic treatments to prevent chronic disease initiation, and 3) treating chronic diseases after they have developed.
AB - Humans are constantly exposed to exogenous chemicals throughout their life, which can lead to a multitude of negative health impacts. Advanced materials can play a key role in preventing or mitigating these impacts through a wide variety of applications. The tunable properties of hydrogels and hydrogel nanocomposites (e.g., swelling behavior, biocompatibility, stimuli responsiveness, functionality, etc.) have deemed them ideal platforms for removal of environmental contaminants, detoxification, and reduction of body burden from exogenous chemical exposures for prevention of disease initiation, and advanced treatment of chronic diseases, including cancer, diabetes, and cardiovascular disease. In this review, three main junctures where the use of hydrogel and hydrogel nanocomposite materials can intervene to positively impact human health are highlighted: 1) preventing exposures to environmental contaminants, 2) prophylactic treatments to prevent chronic disease initiation, and 3) treating chronic diseases after they have developed.
KW - chronic diseases
KW - hydrogel nanocomposites
KW - hydrogels
KW - remediations
KW - therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85120911846&partnerID=8YFLogxK
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U2 - 10.1002/adhm.202101820
DO - 10.1002/adhm.202101820
M3 - Review article
C2 - 34811960
AN - SCOPUS:85120911846
SN - 2192-2640
VL - 11
JO - Advanced healthcare materials
JF - Advanced healthcare materials
IS - 7
M1 - 2101820
ER -