Hyperglycemia: Cell death in a cave

Eric J. Smart, Xiang An Li

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Mitochondria play a central role in mediating high glucose-induced apoptosis. A recent study has shown that increases in glucose levels induce significant alterations in caveolae components, suggesting that high glucose may affect apoptotic signaling initiated in caveolae.

Original languageEnglish
Pages (from-to)524-526
Number of pages3
JournalBiochimica et Biophysica Acta - Molecular Basis of Disease
Volume1772
Issue number5
DOIs
StatePublished - May 2007

Keywords

  • Apoptosis
  • Caveolae
  • Glucose
  • Mitochondria
  • SR-BI

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

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