Abstract
Scoparia dulcis L. commonly known as 'Sweet Broomweed' is widely used in Indian folk medicine for the treatment of diabetes mellitus. Oral administration of 0.15, 0.30 and 0.45 g/kg body weight of the aqueous extract of the Scoparia dulcis leaves (SLEt) for 45 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin and an increase in total haemoglobin but in the case of 0.45 g/kg body weight the effect was highly significant. The aqueous extract also prevented a decrease in the body weight. An oral glucose tolerance test was also performed in experimental diabetic rats, in which there was a significant improvement in glucose tolerance in animals treated with SLEt and the effect was comparable to that of glibenclamide.
Original language | English |
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Pages (from-to) | 662-664 |
Number of pages | 3 |
Journal | Phytotherapy Research |
Volume | 16 |
Issue number | 7 |
DOIs | |
State | Published - Nov 2002 |
Keywords
- Alloxan
- Diabetes
- Hypoglycaemic effect
- Scoparia dulcis
ASJC Scopus subject areas
- Pharmacology