Hypoxanthine Phosphoribosyltransferase cDNA in Gerbils (Meriones unguiculatus)

Zhuming Mai, David W. Horohov, Thomas R. Klei

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Hypoxanthine phosphoribosyltransferase (HPRT) is a purine salvage enzyme that catalyzes conversion of hypoxanthine and guanine to their respective mononucleotides. Because of its ubiquitous nature, HPRT is known as a "housekeeping" gene and has been frequently used as an internal control in reverse transcriptase-polymerase chain reaction (RT-PCR) quantification of cytokine mRNA. Cloning and sequencing of the gerbil HPRT cDNA sequence is an important step in the development of RT-PCR procedures in this model. Two forms of gerbil HPRT cDNA were isolated and molecularly characterized.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalLaboratory Animal Science
Issue number2
StatePublished - 1998

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Veterinary (all)


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