TY - JOUR
T1 - Immunohistochemical staining of cholinergic neurons in the human brain using a polyclonal antibody to human choline acetyltransferase
AU - German, Dwight C.
AU - Bruce, Gordon
AU - Hersh, Louis B.
PY - 1985/10/24
Y1 - 1985/10/24
N2 - Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.
AB - Antibodies against human placental choline acetyltransferase (ChAT) were used to immunohistochemically stain cholinergic neurons in the neostriatum and nucleus basalis of Meynert in human brain. Cells in both regions were intensely stained as were nerve fibers. Comparable cells were stained in these same brain regions in the rat. This anti-human ChAT antibody will enable the further detailed characterization of cholinergic neurons in the human brain in both health and disease.
KW - choline acetyltransferase
KW - human brain
KW - immunohistochemistry
UR - http://www.scopus.com/inward/record.url?scp=0022347355&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022347355&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(85)90391-X
DO - 10.1016/0304-3940(85)90391-X
M3 - Article
C2 - 3908999
AN - SCOPUS:0022347355
SN - 0304-3940
VL - 61
SP - 1
EP - 5
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 1-2
ER -