29 Scopus citations


Immunotherapy is a conceptually attractive approach, because it is highly specific and can deal with disseminated disease with minimal impact on normal tissues. Ability to induce antigen-specific immune responses in patients with lung cancer is now well established in early-phase clinical trials using a variety of immunotherapeutic approaches. Although no immunotherapy is likely to be a panacea, randomized phase IIB studies offer promise of therapeutic activity in both early- and late-stage lung cancer. This review will cover basic concepts of immunotherapy, provide perspective on vaccine development, and update the status of ongoing clinical trials in lung cancer.

Original languageEnglish
Pages (from-to)224-232
Number of pages9
JournalProceedings of the American Thoracic Society
Issue number2
StatePublished - Apr 15 2009


  • Clinical trials
  • Immunotherapy
  • Lung cancer
  • Vaccines

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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