TY - JOUR
T1 - Impact of sulfidation on the bioavailability and toxicity of silver nanoparticles to Caenorhabditis elegans
AU - Starnes, Daniel L.
AU - Unrine, Jason M.
AU - Starnes, Catherine P.
AU - Collin, Blanche E.
AU - Oostveen, Emily K.
AU - Ma, Rui
AU - Lowry, Gregory V.
AU - Bertsch, Paul M.
AU - Tsyusko, Olga V.
N1 - Publisher Copyright:
© 2014 Elsevier Ltd
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Sulfidation is a major transformation product for manufactured silver nanoparticles (Ag-MNPs) in the wastewater treatment process. We studied the dissolution, uptake, and toxicity of Ag-MNP and sulfidized Ag-MNPs (sAg-MNPs) to a model soil organism, Caenorhabditis elegans. Our results show that reproduction was the most sensitive endpoint tested for both Ag-MNPs and sAg-MNPs. We also demonstrate that sulfidation not only decreases solubility of Ag-MNP, but also reduces the bioavailability of intact sAg-MNP. The relative contribution of released Ag+ compared to intact particles to toxicity was concentration dependent. At lower total Ag concentration, a greater proportion of the toxicity could be explained by dissolved Ag, whereas at higher total Ag concentration, the toxicity appeared to be dominated by particle specific effects.
AB - Sulfidation is a major transformation product for manufactured silver nanoparticles (Ag-MNPs) in the wastewater treatment process. We studied the dissolution, uptake, and toxicity of Ag-MNP and sulfidized Ag-MNPs (sAg-MNPs) to a model soil organism, Caenorhabditis elegans. Our results show that reproduction was the most sensitive endpoint tested for both Ag-MNPs and sAg-MNPs. We also demonstrate that sulfidation not only decreases solubility of Ag-MNP, but also reduces the bioavailability of intact sAg-MNP. The relative contribution of released Ag+ compared to intact particles to toxicity was concentration dependent. At lower total Ag concentration, a greater proportion of the toxicity could be explained by dissolved Ag, whereas at higher total Ag concentration, the toxicity appeared to be dominated by particle specific effects.
KW - Bioaccumulation
KW - Nanotechnology
KW - Soil
KW - Transformation
KW - Wastewater treatment
UR - http://www.scopus.com/inward/record.url?scp=84934930231&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84934930231&partnerID=8YFLogxK
U2 - 10.1016/j.envpol.2014.10.009
DO - 10.1016/j.envpol.2014.10.009
M3 - Article
C2 - 25463719
AN - SCOPUS:84934930231
SN - 0269-7491
VL - 196
SP - 239
EP - 246
JO - Environmental Pollution
JF - Environmental Pollution
ER -