In vitro activity of piperacillin, ticarcillin, mezlocillin, ticarcillin-clavulanic acid, aztreonam, ceftazidime, azlocillin, cefoperazone, and thienamycin against Pseudomonas aeruginosa

R. N. Greenberg, M. R. Bollinger, M. R. Alivisatos

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The in vitro susceptibility of 103 well-characterized strains of Pseudomonas aeruginosa to nine antimicrobial agents was assessed by means of the Kirby-Bauer disk diffusion assay and the microtiter minimal inhibitory concentration assay. The antimicrobials, from the most to the least active against P aeruginosa, were thienamycin > ceftazidime > piperacillin > azlocillin > cefoperazone > aztreonam > ticarcillin > ticarcillin-clavulanic acid > mezlocillin. The resistance patterns of the antimicrobial agents suggest that P aeruginosa resistant to a penicillin, cephalosporin, or aztreonam may be susceptible to thienamycin.

Original languageEnglish
Pages (from-to)655-657
Number of pages3
JournalClinical Therapeutics
Volume8
Issue number6
StatePublished - 1986

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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