Numerous studies using a variety of methodologies strongly support the notion that estradiol serves many important nonreproductive functions. In addition to its well-recognized effects on the reproductive axis and traditional reproductive target organs, we now recognize that estradiol is a potent growth and protective factor that acts on multiple regions of the brain, including those not critical to cyclic gonadotropin-releasing hormone (GnRH) release and luteinizing hormone (LH) synthesis and secretion.
|Title of host publication||Neuroplasticity, Development, and Steroid Hormone Action|
|Number of pages||11|
|State||Published - Jan 1 2001|
ASJC Scopus subject areas
- Neuroscience (all)
- Medicine (all)
- Biochemistry, Genetics and Molecular Biology (all)