In vitro and in vivo approaches to the study of the neuroprotective actions of estradiol

Phyllis M. Wise, Melinda E. Wilson, Dena B. Dubal, Shane W. Rau

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Numerous studies using a variety of methodologies strongly support the notion that estradiol serves many important nonreproductive functions. In addition to its well-recognized effects on the reproductive axis and traditional reproductive target organs, we now recognize that estradiol is a potent growth and protective factor that acts on multiple regions of the brain, including those not critical to cyclic gonadotropin-releasing hormone (GnRH) release and luteinizing hormone (LH) synthesis and secretion.

Original languageEnglish
Title of host publicationNeuroplasticity, Development, and Steroid Hormone Action
Pages81-91
Number of pages11
ISBN (Electronic)9781420041194
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Neuroscience (all)
  • Medicine (all)
  • Biochemistry, Genetics and Molecular Biology (all)

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