TY - JOUR
T1 - In vitro pharmacodynamics of anidulafungin and caspofungin against Candida glabrata isolates, including strains with decreased caspofungin susceptibility
AU - Cota, Jason
AU - Carden, Michael
AU - Graybill, John R.
AU - Najvar, Laura K.
AU - Burgess, David S.
AU - Wiederhold, Nathan P.
PY - 2006/11
Y1 - 2006/11
N2 - The activities of anidulafungin and caspofungin against Candida glabrata were evaluated. MICs, 50% inhibitory concentrations (IC50 values), and IC90 values for anidulafungin were lower than those for caspofungin for 16 of 18 strains tested. Anidulafungin has potent in vitro activity against C. glabrata that is maintained against isolates with elevated caspofungin MICs.
AB - The activities of anidulafungin and caspofungin against Candida glabrata were evaluated. MICs, 50% inhibitory concentrations (IC50 values), and IC90 values for anidulafungin were lower than those for caspofungin for 16 of 18 strains tested. Anidulafungin has potent in vitro activity against C. glabrata that is maintained against isolates with elevated caspofungin MICs.
UR - http://www.scopus.com/inward/record.url?scp=33750577895&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750577895&partnerID=8YFLogxK
U2 - 10.1128/AAC.00538-06
DO - 10.1128/AAC.00538-06
M3 - Article
C2 - 16940061
AN - SCOPUS:33750577895
SN - 0066-4804
VL - 50
SP - 3926
EP - 3928
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 11
ER -
