In vivo myocardial material properties and stress distributions in normal and failing human hearts

Jonathan F. Wenk; Zhihong Zhang; Guangming Cheng; Kay Sun; Joseph C. Walker; David A. Saloner; Mark B. Ratcliffe; Julius M. Guccione

doi:10.1007/978-1-4419-6691-9_8

In vivo myocardial material properties and stress distributions in normal and failing human hearts

Jonathan F. Wenk, Zhihong Zhang, Guangming Cheng, Kay Sun, Joseph C. Walker, David A. Saloner, Mark B. Ratcliffe, Julius M. Guccione

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

A noninvasive method for estimating myocardial material properties in vivo would be of great value in the design and evaluation of new surgical and medical strategies to treat and/or prevent heart failure. Once the material properties for the myocardium are established, the effect of therapeutic changes on regional geometry (i.e., surgical remodeling) and/or material properties (i.e., medicine, gene therapy, and cell therapy) can be evaluated and the success or failure of a proposed therapy predicted. With clinical experience, such a method could be used as a diagnostic modality to risk stratify patients early after a myocardial infarction (MI) who are at risk for adverse remodeling and the development of heart failure.

Original language	English
Title of host publication	Patient-Specific Modeling of the Cardiovascular System
Subtitle of host publication	Technology-Driven Personalized Medicine
Pages	131-144
Number of pages	14
ISBN (Electronic)	9781441966919
DOIs	https://doi.org/10.1007/978-1-4419-6691-9_8
State	Published - 2010

ASJC Scopus subject areas

Medicine (all)

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10.1007/978-1-4419-6691-9_8

Cite this

Wenk, J. F., Zhang, Z., Cheng, G., Sun, K., Walker, J. C., Saloner, D. A., Ratcliffe, M. B., & Guccione, J. M. (2010). In vivo myocardial material properties and stress distributions in normal and failing human hearts. In Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine (pp. 131-144) https://doi.org/10.1007/978-1-4419-6691-9_8

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In vivo myocardial material properties and stress distributions in normal and failing human hearts

Abstract

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