A noninvasive method for estimating myocardial material properties in vivo would be of great value in the design and evaluation of new surgical and medical strategies to treat and/or prevent heart failure. Once the material properties for the myocardium are established, the effect of therapeutic changes on regional geometry (i.e., surgical remodeling) and/or material properties (i.e., medicine, gene therapy, and cell therapy) can be evaluated and the success or failure of a proposed therapy predicted. With clinical experience, such a method could be used as a diagnostic modality to risk stratify patients early after a myocardial infarction (MI) who are at risk for adverse remodeling and the development of heart failure.
|Title of host publication||Patient-Specific Modeling of the Cardiovascular System|
|Subtitle of host publication||Technology-Driven Personalized Medicine|
|Number of pages||14|
|State||Published - 2010|
ASJC Scopus subject areas
- Medicine (all)