In vivo myocardial material properties and stress distributions in normal and failing human hearts

Jonathan F. Wenk; Zhihong Zhang; Guangming Cheng; Kay Sun; Joseph C. Walker; David A. Saloner; Mark B. Ratcliffe; Julius M. Guccione

doi:10.1007/978-1-4419-6691-9_8

In vivo myocardial material properties and stress distributions in normal and failing human hearts

Jonathan F. Wenk
, Zhihong Zhang
, Guangming Cheng
, Kay Sun
, Joseph C. Walker
, David A. Saloner
, Mark B. Ratcliffe
, Julius M. Guccione

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

A noninvasive method for estimating myocardial material properties in vivo would be of great value in the design and evaluation of new surgical and medical strategies to treat and/or prevent heart failure. Once the material properties for the myocardium are established, the effect of therapeutic changes on regional geometry (i.e., surgical remodeling) and/or material properties (i.e., medicine, gene therapy, and cell therapy) can be evaluated and the success or failure of a proposed therapy predicted. With clinical experience, such a method could be used as a diagnostic modality to risk stratify patients early after a myocardial infarction (MI) who are at risk for adverse remodeling and the development of heart failure.

Original language	English
Title of host publication	Patient-Specific Modeling of the Cardiovascular System
Subtitle of host publication	Technology-Driven Personalized Medicine
Pages	131-144
Number of pages	14
ISBN (Electronic)	9781441966919
DOIs	https://doi.org/10.1007/978-1-4419-6691-9_8
State	Published - 2010

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media, LLC 2010. All rights reserved.

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4419-6691-9_8

Cite this

Wenk, J. F., Zhang, Z., Cheng, G., Sun, K., Walker, J. C., Saloner, D. A., Ratcliffe, M. B., & Guccione, J. M. (2010). In vivo myocardial material properties and stress distributions in normal and failing human hearts. In Patient-Specific Modeling of the Cardiovascular System: Technology-Driven Personalized Medicine (pp. 131-144) https://doi.org/10.1007/978-1-4419-6691-9_8

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ER -

In vivo myocardial material properties and stress distributions in normal and failing human hearts

Abstract

Bibliographical note

ASJC Scopus subject areas

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