In Vivo voltammetry in drug abuse research

This chapter is intended for those who wish to gain a general knowledge of the principles, materials, and approaches that underlie the current methodologies being used to study drug-abuse issues in central nervous system (CNS) tissues using electrochemical techniques, which are often termed “voltammetric recordings.” We have not tried to be comprehensive in our citation of all literature pertaining to this topic. The interested reader is directed to other reviews and review chapters for a more thorough understanding of the use of these methods. 1-6 We hope that this review will be of value to the numerous scientists who wish to use these methods to study the effects of drugs of abuse on the dynamics of neurotransmitters and neurochemicals in the CNS. In addition, we have included summaries of some of the results to date regarding the use of voltammetric recordings on issues of drug abuse.