Increased buprenorphine dosing frequency was not associated with increased severity of neonatal opioid withdrawal syndrome

Alexander M. Harrison; Cynthia Cockerham; Asmita Shrestha; Gregory S. Hawk; John O’Brien; Barbara V. Parilla

doi:10.1016/j.ajogmf.2026.101944

Increased buprenorphine dosing frequency was not associated with increased severity of neonatal opioid withdrawal syndrome

Alexander M. Harrison
, Cynthia Cockerham
, Asmita Shrestha
, Gregory S. Hawk
, John O’Brien
, Barbara V. Parilla

Research output: Contribution to journal › Letter › peer-review

Original language	English
Article number	101944
Number of pages	3
Journal	American Journal of Obstetrics and Gynecology MFM
Volume	8
Issue number	6
DOIs	https://doi.org/10.1016/j.ajogmf.2026.101944
State	Published - Jun 2026

Funding

Retrospective cohort study. Subjects were identified from a prospectively collected database of obstetric patients with substance use disorder (SUD) enrolled in a multispecialty treatment program from 2014 to 2025. Institutional Review Board approval was obtained from the University of Kentucky (Protocol #43698). Data were collected at each prenatal visit using standardized clinical protocols. The study was supported by grants from the Kentucky Opioid Response Effort (KORE).

Funders
Kentucky Opioid Response Effort

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/j.ajogmf.2026.101944

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title = "Increased buprenorphine dosing frequency was not associated with increased severity of neonatal opioid withdrawal syndrome",

author = "Harrison, \{Alexander M.\} and Cynthia Cockerham and Asmita Shrestha and Hawk, \{Gregory S.\} and John O{\textquoteright}Brien and Parilla, \{Barbara V.\}",

year = "2026",

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doi = "10.1016/j.ajogmf.2026.101944",

language = "English",

volume = "8",

journal = "American Journal of Obstetrics and Gynecology MFM",

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T1 - Increased buprenorphine dosing frequency was not associated with increased severity of neonatal opioid withdrawal syndrome

AU - Harrison, Alexander M.

AU - Cockerham, Cynthia

AU - Shrestha, Asmita

AU - Hawk, Gregory S.

AU - O’Brien, John

AU - Parilla, Barbara V.

PY - 2026/6

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UR - https://www.scopus.com/pages/publications/105040752949#tab=citedBy

U2 - 10.1016/j.ajogmf.2026.101944

DO - 10.1016/j.ajogmf.2026.101944

M3 - Letter

C2 - 42230093

AN - SCOPUS:105040752949

SN - 2589-9333

VL - 8

JO - American Journal of Obstetrics and Gynecology MFM

JF - American Journal of Obstetrics and Gynecology MFM

IS - 6

M1 - 101944

ER -

Increased buprenorphine dosing frequency was not associated with increased severity of neonatal opioid withdrawal syndrome

Funding

ASJC Scopus subject areas

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