Increased Risk of Pulmonary Complications with Long Cephalomedullary Nails in Geriatric Intertrochanteric Femur Fractures

  • Maaz Muhammad
  • , Griffin Green
  • , Wyatt G.S. Southall
  • , Adam N. Musick
  • , Austin T. Gregg
  • , Robert K. Wagner
  • , Gregory S. Hawk
  • , Arun Aneja

Research output: Contribution to journalArticlepeer-review

Abstract

Background: – Despite extensive literature comparing short and long cephalomedullary nails (CMNs), the impact of CMN length on pulmonary complications in geriatric patients with intertrochanteric (IT) fractures is not well established. This study compared postoperative pulmonary complications in geriatric patients with IT fractures treated with short (<235 mm) or intermediate (235-240 mm) CMNs (SINs) versus long (≥300 mm) CMNs (LNs).Methods: – Patients aged ≥65 years with AO Foundation/Orthopaedic Trauma Association (AO/OTA) 31A1–A3 fractures treated with SINs or LNs between 2008 and 2020 were retrospectively identified at a single Level 1 Trauma center. The primary outcome was inpatient postoperative pulmonary complications. Secondary outcomes included mortality, surgical duration, and other inpatient postoperative complications. Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were calculated using logistic regression to adjust for comorbidities (i.e., diabetes, hypertension, chronic) obstructive pulmonary disease, smoking status, age, AO/OTA classification, ASA ≥3, time to surgery, and surgical duration.Results: – Overall, 881 patients were treated with either an SIN (n = 327) or an LN (n = 554). The SIN group was older (80.7 ± 9.1 years vs. 79.3 ± 8.4 years, p = 0.016), had a higher proportion of AO/OTA 31A1 fractures (p < 0.001), and included more patients with ASA ≥3 (89% vs. 84%, p = 0.035). In the SIN group, the median surgical duration was shorter (60 [interquartile range (IQR): 47-79] vs. 81 minutes [IQR: 62-106], p < 0.001), and rates of postoperative anemia (74% vs. 81%, p = 0.017) and transfusion (43% vs. 54%, p = 0.001) were lower. After adjusting for covariates, multivariable analysis demonstrated increased odds of postoperative pneumonia (AOR: 2.09, 95% CI: 1.01-4.71, p = 0.048), pulmonary embolism (AOR: 4.38, 95% CI: 1.09-29.5, p = 0.036), and transfusion (AOR: 1.38, 95% CI: 1.02-1.85, p = 0.034) in the LN group. There were no differences in mortality or other postoperative complications (p > 0.05).Conclusions: – Geriatric patients with IT fractures treated with LNs had increased odds of inpatient postoperative pneumonia, pulmonary embolism, and transfusion. However, mortality and other postoperative complications were similar.Level of Evidence: – Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Original languageEnglish
JournalJBJS Open Access
Volume10
Issue number3
DOIs
StatePublished - 2025

Bibliographical note

Publisher Copyright:
© 2025 The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated. All rights reserved.

Funding

A. Aneja is a paid consultant for DePuy Synthes and Runatek and has received research or institutional support from the Department of Defense, Orthopaedic Trauma Association, American Orthopaedic Foot and Ankle Society, and AO Trauma North America. A. Aneja or an immediate family member is a member of a speaker's bureau or has made paid presentations on behalf of DePuy Synthes and AO Trauma North America. Thuan Ly reports honoraria from the AO foundation and is a paid consultant for DePuy Synthes. R.K. Wagner received support from the Marti-Keuning Eckhardt Foundation (Amsterdam, the Netherlands), the Cultuurfonds (Amsterdam, the Netherlands), the VSB Foundation (Utrecht, the Netherlands), and the Stichting Prof. Michaël-van Vloten Foundation (the Hague, the Netherlands). All remaining authors declare that they have no financial interests. This project was supported by the NIH National Center for Advancing Translational Sciences through grant number UL1TR001998. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

FundersFunder number
VSB Foundation
Marti-Keuning Eckhardt Foundation
Stichting Prof. Michaël-van Vloten Foundation
NIH National Center for Advancing Translational Sciences and Center for Clinical and Translational ScienceUL1TR001998

    ASJC Scopus subject areas

    • Surgery
    • Orthopedics and Sports Medicine

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