Abstract
Background: Lipoprotein lipase regulates fat uptake into adipose tissue. Results: A mouse model with increased adipose tissue lipoprotein lipase has improved glucose metabolism when challenged with a high fat diet. Conclusion: Increasing adipose tissue lipoprotein lipase improves adipose tissue function. Significance: Adipose tissue lipoprotein lipase protects against obesity-induced glucose and insulin intolerance.
| Original language | English |
|---|---|
| Pages (from-to) | 11547-11556 |
| Number of pages | 10 |
| Journal | Journal of Biological Chemistry |
| Volume | 290 |
| Issue number | 18 |
| DOIs | |
| State | Published - May 1 2015 |
Bibliographical note
Publisher Copyright:© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.
Funding
| Funders | Funder number |
|---|---|
| National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences | DK039176, DK071349 |
| National Center for Advancing Translational Sciences (NCATS) | UL1TR000117 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology
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