Infective endocarditis complicated by mitral valve aneurysm: Pathologic and echocardiographic correlations

Arash Seratnahaei, Alison L. Bailey, Patrick J. Hensley, William O'Connor, Mikel D. Smith

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Infective endocarditis is a well-described cardiovascular disease that causes significant morbidity and mortality despite medical and surgical advances. Complications of endocarditis include heart failure, systemic embolization, and valvular destruction including valve aneurysms which increase morbidity and mortality. Mitral valve aneurysms are rarely encountered in the clinical setting. We present eight mitral valve aneurysm cases and discuss a new potential pathogenesis of this deadly endocarditis complication. Pathologic evaluation suggests that neovascularization of the anterior mitral valve leaflet predisposes this territory to abscess and aneurysm formation. In conclusion, mitral valve aneurysms appear to be another form of intravalvular abscess which has expanded and should be approached aggressively with surgical intervention if indicated.

Original languageEnglish
Pages (from-to)1417-1422
Number of pages6
Issue number9
StatePublished - Sep 1 2015

Bibliographical note

Publisher Copyright:
© 2015, Wiley Periodicals, Inc.


  • echocardiography
  • infective endocarditis
  • mitral valve aneurysm

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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