Abstract
It has been increasingly recognized that tumor microenvironment plays an important role in carcinogenesis. Inflammatory component is present and contributes to tumor proliferation, angiogenesis, metastasis and resistance to hormonal and chemotherapy. This review highlights the role of inflammation in the tumor metastasis. We focus on the function of proinflammatory factors, particularly cytokines during tumor metastasis. Understanding of the mechanisms by which inflammation contributes to metastasis will lead to innovative approach for treating cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 3267-3273 |
| Number of pages | 7 |
| Journal | Cell Cycle |
| Volume | 8 |
| Issue number | 20 |
| DOIs | |
| State | Published - Oct 15 2009 |
Keywords
- Epithelial-mesenchymal transition
- Inflammation
- Metastasis
ASJC Scopus subject areas
- Molecular Biology
- Developmental Biology
- Cell Biology
