Abstract
PURPOSE OF REVIEW: This article will summarize recent observations that provide mechanistic insight into the molecular and cellular links between inflammation and thrombosis in the context of cardiovascular and other thromboinflammatory disease states. RECENT FINDINGS: Several disease conditions are characterized by a thromboinflammatory state in which interactions of blood cells and components with the vascular wall perpetuate both thrombotic and inflammatory pathways. Targeting these pathways may be of benefit in inflammatory conditions and cardiovascular disease. SUMMARY: Ongoing clinical trials should provide additional insight into the hypothesis that the thromboinflammatory state contributes to adverse clinical outcomes.
| Original language | English |
|---|---|
| Pages (from-to) | 457-463 |
| Number of pages | 7 |
| Journal | Current Opinion in Hematology |
| Volume | 20 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2013 |
Funding
| Funders | Funder number |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | R00HL122505 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- cardiovascular disease
- inflammation
- thrombosis
ASJC Scopus subject areas
- Hematology
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