Inflammation is a beneficial response that can remove pathogens, repair injured tissue and restore homeostasis to damaged tissues and organs. However, increasing evidence indicate that chronic inflammation plays a pivotal role in tumor development, as well as progression, metastasis, and resistance to chemotherapy. We will review the current knowledge regarding the contribution of inflammation to epithelial mesenchymal transition. We will also provide some perspectives on the relationship between ER-stress signals and metabolism, and the role of these processes in the development of inflammation.
|Number of pages||9|
|Journal||Current Pharmaceutical Design|
|State||Published - Jun 1 2015|
Bibliographical notePublisher Copyright:
© 2015 Bentham Science Publishers.
- Epithelial-mesenchymal transition
ASJC Scopus subject areas
- Drug Discovery