Influence of depression and gender on symptom burden among patients with advanced heart failure: Insight from the pain assessment, incidence and nature in heart failure study

Christine A. Haedtke, Debra K. Moser, Susan J. Pressler, Misook L. Chung, Sue Wingate, Sarah J. Goodlin

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Introduction: Patients with advanced heart failure (HF) experience many burdensome symptoms that increase patient suffering. Methods: Comparative secondary analysis of 347 patients with advanced HF. Symptom burden was measured with the Memorial Symptom Assessment Scale-HF. Depression was measured using the Patient Health Questionnaire-9. Results: Mean number of symptoms was 13.6. The three most frequent symptoms were non-cardiac pain, shortness of breath, and lack of energy. Patients with depression reported higher symptom burden. Symptom burden differed when compared by gender. Women reported higher symptom burden for other pain, dry mouth, swelling of the arms and legs, sweats, feeling nervous, nausea, and vomiting. Men reported higher symptom burden with sexual problems. Conclusions: Given the high rates of symptoms and distress, interventions are needed to alleviate the symptom burden of patients with advanced HF. Reported symptom burden in patients with advanced heart failure was higher when depressive symptoms were present. Women reported varied number and severity of symptoms than men.

Original languageEnglish
Pages (from-to)201-207
Number of pages7
JournalHeart and Lung
Volume48
Issue number3
DOIs
StatePublished - May 1 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.

Funding

This is a secondary analysis of the data collected in the Pain Assessment, Incidence and Nature in Heart Failure study funded by the Mayday Fund. Clinical Trials number NCT00444301. The writing of this is manuscript was supported by National Institutes of Health, [T32 HL091812 and K12 HL133310-02] This is a secondary analysis of the data collected in the Pain Assessment, Incidence and Nature in Heart Failure study funded by the Mayday Fund . Clinical Trials number NCT00444301 . The writing of this is manuscript was supported by National Institutes of Health , [ T32 HL091812 and K12 HL133310-02 ]

FundersFunder number
National Institutes of Health (NIH)T32 HL091812, K12 HL133310-02
MAYDAY FundNCT00444301

    Keywords

    • Advanced heart failure
    • Depression
    • Gender
    • Memorial Symptom Assessment Scale-heart failure
    • Pain

    ASJC Scopus subject areas

    • Pulmonary and Respiratory Medicine
    • Critical Care and Intensive Care Medicine
    • Cardiology and Cardiovascular Medicine

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