Influence of hydrocortisone acetate on pancreas and mucosal weight, amylase and disaccharidase activities in 14-day-old pigs

K. K. Kreikemeier, D. L. Harmonj, J. L. Nelssen

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

1. 1. One litter of 12 pigs was used to evaluate the effects of hydrocortisone acetate injection on organ weight and carbohydrase activities. 2. 2. Pigs were injected with hydrocortisone acetate or an equal volume of saline at 7 days of age and killed at 14 days, and tissues were collected, weighed, and analyzed for carbohydrase activities. 3. 3. Hydrocortisone had no effect (P > O.40) on daily gain, liver weight, spleen weight, or small intestinal length. 4. 4. Hydrocortisone increased pancreatic weight by 29% and total pancreatic α-amylase content by 38%. 5. 5. Hydrocortisone increased duodenal mucosal weight by 23%, duodenal lactase activity by 44%, duodenal maltase activity by 163%, and duodenal sucrase activity by 214%.

Original languageEnglish
Pages (from-to)45-50
Number of pages6
JournalComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Volume97
Issue number1
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Physiology

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