Abstract
Objectives: The goal was to compare static versus dynamic bone-implant interface histology of mini-screws and to evaluate its relation to diameter and load. Setting and Sample Population: Canine animal model. Material and Methods: Custom-machined, titanium alloy (Ti6AI4V) mini-screws (n = 70) of 1.60, 2.00, 3.00 and 3.75 mm diameter were placed into edentulous sites in five skeletally mature beagle dogs. Using a split-mouth design, no load (NL) was applied to one side while a 2N load (L) was applied by calibrated coil springs on the other side. Intravenous bone labels were administered 21 and 7 days prior to sacrifice. Dogs were euthanized 90 days after screw placement. Bone sections were analysed under bright-field and epifluorescent light. The region of interest was defined as the bone within the threads of the screws. The following parameters were quantified: (a) Static—bone volume/tissue volume (BV/TV %) and bone-implant contact (BIC, %); (b) Dynamic—labelled bone/bone volume (LB/BV, %), and dynamic BIC (DBIC, %). Results: BV/TV ranged from 71.2% to 85.0% of the screw surface. BIC ranged from 45.7% to 55.4% of the screw surface and was not affected by diameter (P = 0.66). In contrast, the percentage of DBIC did not vary with the applied load (P = 0.41); however, it correlated significantly with the diameter of the screw (P = 0.001). Conclusion: The percentage of DBIC that is actively remodelling increases with increasing diameter of the screw. Dynamic histomorphometry is more sensitive to detecting changes in bone-implant contact when compared to static measurements.
Original language | English |
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Pages (from-to) | 96-100 |
Number of pages | 5 |
Journal | Orthodontics and Craniofacial Research |
Volume | 22 |
Issue number | S1 |
DOIs | |
State | Published - May 2019 |
Bibliographical note
Publisher Copyright:© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Keywords
- bone histomorphometry
- bone-implant contact
- mini-implant
- mini-screw
ASJC Scopus subject areas
- Orthodontics
- Surgery
- Oral Surgery
- Otorhinolaryngology