Inhibition of fusarium oxysporum F. Sp. nicotianae growth by phenylpropanoid pathway intermediates

Timothy E. Shull, Jasmina Kurepa, Robert D. Miller, Natalia Martinez-Ochoa, Jan A. Smalle

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Fusarium wilt in tobacco caused by the fungus Fusari-um oxysporum f. sp. nicotianae is a disease-management challenge worldwide, as there are few effective and environmentally benign chemical agents for its control. This challenge results in substantial losses in both the quality and yield of tobacco products. Based on an in vitro analysis of the effects of different phenylpropanoid intermediates, we found that the early intermediates trans-cinnamic acid and para-coumaric acid effectively inhibit the mycelial growth of F. oxysporum f. sp. nicoti-anae strain FW316F, whereas the downstream intermediates quercetin and caffeic acid exhibit no fungicidal properties. Therefore, our in vitro screen suggests that trans-cinnamic acid and para-coumaric acid are prom-ising chemical agents and natural lead compounds for the suppression of F. oxysporum f. sp. nicotianae growth.

Original languageEnglish
Pages (from-to)637-642
Number of pages6
JournalPlant Pathology Journal
Volume36
Issue number6
DOIs
StatePublished - 2020

Bibliographical note

Publisher Copyright:
© The Korean Society of Plant Pathology.

Keywords

  • Fungicidal
  • Fusarium oxysporum
  • Para-coumar-ic acid
  • Tobacco
  • Trans-cinnamic acid

ASJC Scopus subject areas

  • Agronomy and Crop Science

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