Insomnia and chronic heart failure

Don Hayes, Michael I. Anstead, Julia Ho, Barbara A. Phillips

Research output: Contribution to journalReview articlepeer-review

48 Scopus citations


Insomnia is highly prevalent in patients with chronic disease including chronic heart failure (CHF) and is a significant contributing factor to fatigue and poor quality of life. The pathophysiology of CHF often leads to fatigue, due to nocturnal symptoms causing sleep disruption, including cough, orthopnea, paroxysmal nocturnal dyspnea, and nocturia. Inadequate cardiac function may lead to hypoxemia or poor perfusion of the cerebrum, skeletal muscle, or visceral body organs, which result in organ dysfunction or failure and may contribute to fatigue. Sleep disturbances negatively affect all dimensions of quality of life and is related to increased risk of comorbidities, including depression. This article reviews insomnia in CHF, cardiac medication side-effects related to sleep disturbances, and treatment options.

Original languageEnglish
Pages (from-to)171-182
Number of pages12
JournalHeart Failure Reviews
Issue number3
StatePublished - 2009


  • Chronic heart failure
  • Fatigue
  • Insomnia
  • Medication
  • Sleep disturbance

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Insomnia and chronic heart failure'. Together they form a unique fingerprint.

Cite this