Integrative technique for the determination of QT interval

Mohamed A. Mneimneh, R. J. Povinelli, M. T. Johnson

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations


The 2006 Physionet/Computers in Cardiology Challenge is motivated by the expected requirement of regulatory agencies for skilled readers to conduct QT duration studies of all drugs in clinical trials. However, clinically valid automatic methods would reduce the cost and time need to conduct such QT studies, which are crucial in determining potential proarrhythmic side effects, such as torsade de pointes, of non-antiarrhythmic drugs. The challenge dataset is the PTB Diagnostic ECG Database, which consists of 549 records from 294 subjects. This work proposes an integrative approach for the identification of the PQ junction and T-end of the QT interval. This novel approach uses the curvature of the Q-wave and the T-wave in order to identify an accurate isoelectric curve, between two consecutive peaks, that intersects the extremities of the features. The score for the challenge is 35.19 ms for this method compared to top score of 17.33 ms.

Original languageEnglish
Title of host publication2006 Computers in Cardiology, CIC
Number of pages4
StatePublished - 2006
Event2006 Computers in Cardiology, CIC - Valencia, Spain
Duration: Sep 17 2006Sep 20 2006

Publication series

NameComputers in Cardiology
ISSN (Print)0276-6574


Conference2006 Computers in Cardiology, CIC

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine


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