Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: A general strategy toward drug delivery vehicles

Vincent J. Venditto, Kimberly Allred, Clinton D. Allred, Eric E. Simanek

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

The camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

Original languageEnglish
Pages (from-to)5541-5542
Number of pages2
JournalChemical Communications
Issue number37
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry (all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: A general strategy toward drug delivery vehicles'. Together they form a unique fingerprint.

Cite this