Abstract
Fractional intestinal absorption of Ca (A(ca)) and fractional whole body retention of Ca (R(ca)) were measured in 130 patients with incipient and advanced renal failure. In fasting patients without prior dietary restrictions, A(ca) was measured with a 47Ca double-dose technique using a whole body counter. A(ca) was significantly decreased and R(ca) significantly increased in patients with renal failure. A significant correlation between GFR and A(ca) was observed. A defect of Ca absorption was found in some patients with 75 ml/min x 1.73 m2 GFR, earlier than reported by previous investigators. R(ca) increased with decreasing GFR and correlated to serum PTH and histological parameters of PTH action on bone. It is suggested that R(ca) represents a useful indicator of bone turnover.
| Original language | English |
|---|---|
| Pages (from-to) | 263-270 |
| Number of pages | 8 |
| Journal | Mineral and Electrolyte Metabolism |
| Volume | 1 |
| Issue number | 5 |
| State | Published - 1978 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Biochemistry
