Intra- and extracellular water dynamics on rehydration in cholera and noncholera patients

Mohammed I. Hossain; Iqbal Kabir; George J. Fuchs; Martin J. Mccutcheon; Jose O. Alvarez; Mohammed A. Khaled

doi:10.1023/A:1018891914622

Intra- and extracellular water dynamics on rehydration in cholera and noncholera patients

Mohammed I. Hossain, Iqbal Kabir, George J. Fuchs, Martin J. Mccutcheon, Jose O. Alvarez, Mohammed A. Khaled

Research output: Contribution to journal › Article › peer-review

Abstract

To estimate the intra- and extracellular body water compartments during rehydration of patients with cholera and noncholera diarrhea by bioimpedance analyzer, we studied 30 patients with acute watery diarrhea. Total body water (TBW), intracellular water (ICW), and extracellular water (ECW) of severely dehydrated adult patients were measured with a dual frequency bioimpedance analyzer at different phases of rehydration. Fluid compartments between cholera and noncholera patients were compared. Cholera patients gained more TBW than noncholera patients during recovery. Unlike patients with noncholera diarrhea, the gain in cholera patients was mainly contributed by the ICW (1.5 ± 1.6 vs 3.0 ± 1.2 liters, respectively, P < 0.01). It was also observed that the recovery of the ICW compartment in cholera patients occurred rapidly within the first 2 hr after infusion. Differential dynamics of body water compartments in cholera compared to noncholera patients as observed in this study may contribute further to understanding the mechanism of dehydration in diarrheal disease, which might help in improving case management.

Original language	English
Pages (from-to)	663-667
Number of pages	5
Journal	Digestive Diseases and Sciences
Volume	43
Issue number	3
DOIs	https://doi.org/10.1023/A:1018891914622
State	Published - 1998

Bibliographical note

Funding Information:
This research was supported by ICDDR,B. The ICD-DR,B is supported by agencies and countries which share its concern for the health problems of developing countries.

Keywords

Bioimpedance
Cholera
Extracellular water
Intracellular water
Water dynamics

ASJC Scopus subject areas

Physiology
Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1023/A:1018891914622

Cite this

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title = "Intra- and extracellular water dynamics on rehydration in cholera and noncholera patients",

abstract = "To estimate the intra- and extracellular body water compartments during rehydration of patients with cholera and noncholera diarrhea by bioimpedance analyzer, we studied 30 patients with acute watery diarrhea. Total body water (TBW), intracellular water (ICW), and extracellular water (ECW) of severely dehydrated adult patients were measured with a dual frequency bioimpedance analyzer at different phases of rehydration. Fluid compartments between cholera and noncholera patients were compared. Cholera patients gained more TBW than noncholera patients during recovery. Unlike patients with noncholera diarrhea, the gain in cholera patients was mainly contributed by the ICW (1.5 ± 1.6 vs 3.0 ± 1.2 liters, respectively, P < 0.01). It was also observed that the recovery of the ICW compartment in cholera patients occurred rapidly within the first 2 hr after infusion. Differential dynamics of body water compartments in cholera compared to noncholera patients as observed in this study may contribute further to understanding the mechanism of dehydration in diarrheal disease, which might help in improving case management.",

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author = "Hossain, {Mohammed I.} and Iqbal Kabir and Fuchs, {George J.} and Mccutcheon, {Martin J.} and Alvarez, {Jose O.} and Khaled, {Mohammed A.}",

note = "Funding Information: This research was supported by ICDDR,B. The ICD-DR,B is supported by agencies and countries which share its concern for the health problems of developing countries.",

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AU - Kabir, Iqbal

AU - Fuchs, George J.

AU - Mccutcheon, Martin J.

AU - Alvarez, Jose O.

AU - Khaled, Mohammed A.

N1 - Funding Information: This research was supported by ICDDR,B. The ICD-DR,B is supported by agencies and countries which share its concern for the health problems of developing countries.

PY - 1998

Y1 - 1998

N2 - To estimate the intra- and extracellular body water compartments during rehydration of patients with cholera and noncholera diarrhea by bioimpedance analyzer, we studied 30 patients with acute watery diarrhea. Total body water (TBW), intracellular water (ICW), and extracellular water (ECW) of severely dehydrated adult patients were measured with a dual frequency bioimpedance analyzer at different phases of rehydration. Fluid compartments between cholera and noncholera patients were compared. Cholera patients gained more TBW than noncholera patients during recovery. Unlike patients with noncholera diarrhea, the gain in cholera patients was mainly contributed by the ICW (1.5 ± 1.6 vs 3.0 ± 1.2 liters, respectively, P < 0.01). It was also observed that the recovery of the ICW compartment in cholera patients occurred rapidly within the first 2 hr after infusion. Differential dynamics of body water compartments in cholera compared to noncholera patients as observed in this study may contribute further to understanding the mechanism of dehydration in diarrheal disease, which might help in improving case management.

AB - To estimate the intra- and extracellular body water compartments during rehydration of patients with cholera and noncholera diarrhea by bioimpedance analyzer, we studied 30 patients with acute watery diarrhea. Total body water (TBW), intracellular water (ICW), and extracellular water (ECW) of severely dehydrated adult patients were measured with a dual frequency bioimpedance analyzer at different phases of rehydration. Fluid compartments between cholera and noncholera patients were compared. Cholera patients gained more TBW than noncholera patients during recovery. Unlike patients with noncholera diarrhea, the gain in cholera patients was mainly contributed by the ICW (1.5 ± 1.6 vs 3.0 ± 1.2 liters, respectively, P < 0.01). It was also observed that the recovery of the ICW compartment in cholera patients occurred rapidly within the first 2 hr after infusion. Differential dynamics of body water compartments in cholera compared to noncholera patients as observed in this study may contribute further to understanding the mechanism of dehydration in diarrheal disease, which might help in improving case management.

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Intra- and extracellular water dynamics on rehydration in cholera and noncholera patients

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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