Intra-Lot and Inter-Lot Variability in Cosyntropin.

PJ Almeter; JT Isaacs; Samuel A. Hunter; BS Henderson; RA Lodder

doi:10.6084/m9.figshare.17363048

Intra-Lot and Inter-Lot Variability in Cosyntropin.

PJ Almeter, JT Isaacs, Samuel A. Hunter, BS Henderson, RA Lodder

Research output: Contribution to journal › Article › peer-review

Abstract

Intra-lot and inter-lot variability in cosyntropin was detected in the DQS using Fourier transform near-infrared spectrometry. One vial of 12 sampled from Sandoz Lot0200062 appeared 6.9 SDs from the center of the rest of the vials, and another was 4.3 SDs away. Spectra of 102 vials from 7 lots in the library clustered in two groups (p=0.02).

Original language	English
Number of pages	9
Journal	Contact in context
Volume	2021
DOIs	https://doi.org/10.6084/m9.figshare.17363048
State	Published - Dec 20 2021

Access to Document

10.6084/m9.figshare.17363048

Cite this

@article{a97b7b100d824cdb9997b4dd81045551,

title = "Intra-Lot and Inter-Lot Variability in Cosyntropin.",

abstract = "Intra-lot and inter-lot variability in cosyntropin was detected in the DQS using Fourier transform near-infrared spectrometry. One vial of 12 sampled from Sandoz Lot0200062 appeared 6.9 SDs from the center of the rest of the vials, and another was 4.3 SDs away. Spectra of 102 vials from 7 lots in the library clustered in two groups (p=0.02).",

author = "PJ Almeter and JT Isaacs and Hunter, {Samuel A.} and BS Henderson and RA Lodder",

year = "2021",

month = dec,

day = "20",

doi = "10.6084/m9.figshare.17363048",

language = "English",

volume = "2021",

}

TY - JOUR

T1 - Intra-Lot and Inter-Lot Variability in Cosyntropin.

AU - Almeter, PJ

AU - Isaacs, JT

AU - Hunter, Samuel A.

AU - Henderson, BS

AU - Lodder, RA

PY - 2021/12/20

Y1 - 2021/12/20

N2 - Intra-lot and inter-lot variability in cosyntropin was detected in the DQS using Fourier transform near-infrared spectrometry. One vial of 12 sampled from Sandoz Lot0200062 appeared 6.9 SDs from the center of the rest of the vials, and another was 4.3 SDs away. Spectra of 102 vials from 7 lots in the library clustered in two groups (p=0.02).

AB - Intra-lot and inter-lot variability in cosyntropin was detected in the DQS using Fourier transform near-infrared spectrometry. One vial of 12 sampled from Sandoz Lot0200062 appeared 6.9 SDs from the center of the rest of the vials, and another was 4.3 SDs away. Spectra of 102 vials from 7 lots in the library clustered in two groups (p=0.02).

U2 - 10.6084/m9.figshare.17363048

DO - 10.6084/m9.figshare.17363048

M3 - Article

C2 - 35035309

SN - 1547-8890

VL - 2021

JO - Contact in context

JF - Contact in context

ER -

Intra-Lot and Inter-Lot Variability in Cosyntropin.

Abstract

Access to Document

Fingerprint

Cite this