Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Henrietta S. Bada, John E. Miller, James A. Menke, Thomas G. Menten, Mohammed Bashiru, David Binstadt, David S. Sumner, Narinder N. Khanna

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

Original languageEnglish
Pages (from-to)291-296
Number of pages6
JournalJournal of Pediatrics
Volume100
Issue number2
DOIs
StatePublished - Feb 1982

Bibliographical note

Funding Information:
From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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