Abstract
We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.
| Original language | English |
|---|---|
| Pages (from-to) | 291-296 |
| Number of pages | 6 |
| Journal | Journal of Pediatrics |
| Volume | 100 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1982 |
Bibliographical note
Funding Information:From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health