Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Henrietta S. Bada; John E. Miller; James A. Menke; Thomas G. Menten; Mohammed Bashiru; David Binstadt; David S. Sumner; Narinder N. Khanna

doi:10.1016/S0022-3476(82)80657-4

Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Henrietta S. Bada, John E. Miller, James A. Menke, Thomas G. Menten, Mohammed Bashiru, David Binstadt, David S. Sumner, Narinder N. Khanna

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

Original language	English
Pages (from-to)	291-296
Number of pages	6
Journal	Journal of Pediatrics
Volume	100
Issue number	2
DOIs	https://doi.org/10.1016/S0022-3476(82)80657-4
State	Published - Feb 1982

Bibliographical note

Funding Information:
From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

Funding

From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

Funders	Funder number
Illinois Heart Association
Southern Illinois University Edwardsville

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.1016/S0022-3476(82)80657-4

Cite this

@article{b4c8c72ab1724ecea323537f356ae69d,

title = "Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage",

abstract = "We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6\%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.",

author = "Bada, \{Henrietta S.\} and Miller, \{John E.\} and Menke, \{James A.\} and Menten, \{Thomas G.\} and Mohammed Bashiru and David Binstadt and Sumner, \{David S.\} and Khanna, \{Narinder N.\}",

note = "Funding Information: From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address.{"} Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.",

year = "1982",

month = feb,

doi = "10.1016/S0022-3476(82)80657-4",

language = "English",

volume = "100",

pages = "291--296",

number = "2",

}

TY - JOUR

T1 - Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

AU - Bada, Henrietta S.

AU - Miller, John E.

AU - Menke, James A.

AU - Menten, Thomas G.

AU - Bashiru, Mohammed

AU - Binstadt, David

AU - Sumner, David S.

AU - Khanna, Narinder N.

N1 - Funding Information: From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

PY - 1982/2

Y1 - 1982/2

N2 - We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

AB - We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

UR - http://www.scopus.com/inward/record.url?scp=0020085838&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020085838&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(82)80657-4

DO - 10.1016/S0022-3476(82)80657-4

M3 - Article

C2 - 6977024

AN - SCOPUS:0020085838

SN - 0022-3476

VL - 100

SP - 291

EP - 296

JO - Journal of Pediatrics

JF - Journal of Pediatrics

IS - 2

ER -

Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this