Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Henrietta S. Bada; John E. Miller; James A. Menke; Thomas G. Menten; Mohammed Bashiru; David Binstadt; David S. Sumner; Narinder N. Khanna

doi:10.1016/S0022-3476(82)80657-4

Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Henrietta S. Bada
, John E. Miller
, James A. Menke
, Thomas G. Menten
, Mohammed Bashiru
, David Binstadt
, David S. Sumner
, Narinder N. Khanna

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

Original language	English
Pages (from-to)	291-296
Number of pages	6
Journal	Journal of Pediatrics
Volume	100
Issue number	2
DOIs	https://doi.org/10.1016/S0022-3476(82)80657-4
State	Published - Feb 1982

Bibliographical note

Funding Information:
From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

Funding

From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

Funders
Illinois Heart Association
Southern Illinois University Edwardsville

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(82)80657-4

Cite this

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title = "Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage",

abstract = "We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6\%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.",

author = "Bada, \{Henrietta S.\} and Miller, \{John E.\} and Menke, \{James A.\} and Menten, \{Thomas G.\} and Mohammed Bashiru and David Binstadt and Sumner, \{David S.\} and Khanna, \{Narinder N.\}",

note = "Funding Information: From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address.{"} Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.",

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doi = "10.1016/S0022-3476(82)80657-4",

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AU - Bada, Henrietta S.

AU - Miller, John E.

AU - Menke, James A.

AU - Menten, Thomas G.

AU - Bashiru, Mohammed

AU - Binstadt, David

AU - Sumner, David S.

AU - Khanna, Narinder N.

N1 - Funding Information: From the Section on Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Center for the Health Sciences; Division of Statistics and Measurements, and Department of Pediatrics, Radiology and Surgery, Southern Illinois University School of Medicine, and the High-Risk Neonatal Center. Supported in part by Southern Illinois University and Illinois Heart Association. Presented in part at the 1980 Birth Defects Conference, New York, June 9 to 11, 1980. *Reprint address." Newborn Center, 853 Jefferson, 3rd floor, Memphis, TN 38163.

PY - 1982/2

Y1 - 1982/2

N2 - We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

AB - We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVH. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P<0.0002) and increased pulsatility indices (P<0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

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Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

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