TY - JOUR
T1 - INTRACRANIAL PRESSURE REGULATION
T2 - QUANTITATIVE ASSESSMENT OF OUTFLOW RESISTANCE, FLUID FORMATION, AND INTRACRANIAL COMPLIANCE.
AU - Johnson, R. N.
AU - Mann, J. D.
AU - Maffeo, C. J.
AU - Kasarskis, E. J.
AU - Butler, A. B.
AU - Bass, N. H.
PY - 1979
Y1 - 1979
N2 - A quantitative model of the cerebrospinal fluid (CSF) system was derived from manometric data using low volume, short duration infusions into the subarchnoid space in order to describe the mechanisms governing intracranial pressure dynamics. The model suggests that increases in intracranial pressure (ICP) are partially buffered by a nonlinear, pressure dependent outflow resistance to cSF absorption and by a pressure sensitive formation rate of CSF. In contrast, intracranial compliance acts only to buffer transient changes in volume prior to the establishment of steady-state CSF pressures.
AB - A quantitative model of the cerebrospinal fluid (CSF) system was derived from manometric data using low volume, short duration infusions into the subarchnoid space in order to describe the mechanisms governing intracranial pressure dynamics. The model suggests that increases in intracranial pressure (ICP) are partially buffered by a nonlinear, pressure dependent outflow resistance to cSF absorption and by a pressure sensitive formation rate of CSF. In contrast, intracranial compliance acts only to buffer transient changes in volume prior to the establishment of steady-state CSF pressures.
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M3 - Article
AN - SCOPUS:85040154740
JO - Modeling and Simulation, Proceedings of the Annual Pittsburgh Conference
JF - Modeling and Simulation, Proceedings of the Annual Pittsburgh Conference
ER -