Intraindividual variability in cortisol: Approaches, illustrations, and recommendations

Suzanne C. Segerstrom; Sandra E. Sephton; Philip M. Westgate

doi:10.1016/j.psyneuen.2017.01.026

Intraindividual variability in cortisol: Approaches, illustrations, and recommendations

Suzanne C. Segerstrom, Sandra E. Sephton, Philip M. Westgate

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Most of the variance in diurnal cortisol is attributable to intraindividual variability (IIV), defined as relatively short-term, reversible changes. Multiple methods for measuring IIV have been proposed, and some have already been applied to cortisol IIV. In the present review, measurement methods are described and applied to simulated cortisol data with known underlying differences in IIV and to real cortisol data from first-year law students. More slope variance and more residual or net variance were well captured by their individual standard deviations. Explorations of reliability suggested that 10 slopes and 50 residuals result in reliable and stable estimates of the individual standard deviations. A data-analytic plan for cortisol IIV is provided.

Original language	English
Pages (from-to)	114-124
Number of pages	11
Journal	Psychoneuroendocrinology
Volume	78
DOIs	https://doi.org/10.1016/j.psyneuen.2017.01.026
State	Published - Apr 1 2017

Bibliographical note

Funding Information:
This work was made possible by funding from the National Institutes of Health (K02-AG033629, R01-MH61531).

Publisher Copyright:
© 2017 Elsevier Ltd

Keywords

Autocorrelation
Cortisol
Intraindividual variability
Reliability
Root mean squared successive difference
Standard deviation

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.psyneuen.2017.01.026

Cite this

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abstract = "Most of the variance in diurnal cortisol is attributable to intraindividual variability (IIV), defined as relatively short-term, reversible changes. Multiple methods for measuring IIV have been proposed, and some have already been applied to cortisol IIV. In the present review, measurement methods are described and applied to simulated cortisol data with known underlying differences in IIV and to real cortisol data from first-year law students. More slope variance and more residual or net variance were well captured by their individual standard deviations. Explorations of reliability suggested that 10 slopes and 50 residuals result in reliable and stable estimates of the individual standard deviations. A data-analytic plan for cortisol IIV is provided.",

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AU - Sephton, Sandra E.

AU - Westgate, Philip M.

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AB - Most of the variance in diurnal cortisol is attributable to intraindividual variability (IIV), defined as relatively short-term, reversible changes. Multiple methods for measuring IIV have been proposed, and some have already been applied to cortisol IIV. In the present review, measurement methods are described and applied to simulated cortisol data with known underlying differences in IIV and to real cortisol data from first-year law students. More slope variance and more residual or net variance were well captured by their individual standard deviations. Explorations of reliability suggested that 10 slopes and 50 residuals result in reliable and stable estimates of the individual standard deviations. A data-analytic plan for cortisol IIV is provided.

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KW - Reliability

KW - Root mean squared successive difference

KW - Standard deviation

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Intraindividual variability in cortisol: Approaches, illustrations, and recommendations

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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