TY - JOUR
T1 - Investigating the mechanisms of massage efficacy
T2 - The role of mechanical immunomodulation
AU - Waters-Banker, Christine
AU - Dupont-Versteegden, Esther E.
AU - Kitzman, Patrick H.
AU - Butterfield, Timothy A.
PY - 2014
Y1 - 2014
N2 - Massage has the potential to attenuate the inflammatory process, facilitate early recovery, and provide pain relief from muscular injuries. In this hypothesis-driven paper, we integrate the concept of mechanotransduction with the application of massage to explore beneficial mechanisms. By altering signaling pathways involved with the inflammatory process, massage may decrease secondary injury, nerve sensitization, and collateral sprouting, resulting in increased recovery from damage and reduction or prevention of pain. Our goal is to provide a framework that describes our current understanding of the mechanisms whereby massage therapy activates potentially beneficial immunomodulatory pathways.
AB - Massage has the potential to attenuate the inflammatory process, facilitate early recovery, and provide pain relief from muscular injuries. In this hypothesis-driven paper, we integrate the concept of mechanotransduction with the application of massage to explore beneficial mechanisms. By altering signaling pathways involved with the inflammatory process, massage may decrease secondary injury, nerve sensitization, and collateral sprouting, resulting in increased recovery from damage and reduction or prevention of pain. Our goal is to provide a framework that describes our current understanding of the mechanisms whereby massage therapy activates potentially beneficial immunomodulatory pathways.
KW - Afferent nerves
KW - Apoptotic signaling
KW - Inflammation
KW - Macrophages
KW - Mechanotransduction
KW - Neutrophils
KW - Nociception
KW - Sensitization
UR - http://www.scopus.com/inward/record.url?scp=84898640832&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84898640832&partnerID=8YFLogxK
U2 - 10.4085/1062-6050-49.2.25
DO - 10.4085/1062-6050-49.2.25
M3 - Review article
C2 - 24641083
AN - SCOPUS:84898640832
SN - 1062-6050
VL - 49
SP - 266
EP - 273
JO - Journal of Athletic Training
JF - Journal of Athletic Training
IS - 2
ER -