Isolated Histoplasma capsulatum meningoencephalitis in an immunocompetent child

Zachary D. Threlkeld, Robert Broughton, Gulam Q. Khan, Joseph R. Berger

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Histoplasmosis with central nervous system involvement typically arises in the immunocompromised patient with disseminated fungal disease. Rarely, neurologic histoplasmosis may arise as an isolated syndrome in immunocompetent individuals without evidence of general dissemination. The disease often is diagnostically challenging, and a high index of suspicion is required for diagnosis. We describe an immunocompetent 13-year-old girl with atypical symptoms and unusual radiologic findings due to laboratory-confirmed histoplasma meningoencephalitis. She responded well to antifungal therapy.

Original languageEnglish
Pages (from-to)532-535
Number of pages4
JournalJournal of Child Neurology
Issue number4
StatePublished - Apr 2012


  • encephalitis
  • fungal meningitis
  • histoplasmosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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