Large-scale programmed genome rearrangements in vertebrates

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

In some species, large-scale rearrangements occur in a tightly regulated manner, as a normal part of development. This phenomenon, broadly termed programmed genome rearrangement (PGR), is known have evolved independently in several eukaryotic lineages, including ciliated protozoans, some species of roundworms, copepod crustaceans, sciarid flies, and midges. The repeated evolution of PGR suggests recurrent selection for regulated dynamism of genome primary structure.

Original languageEnglish
Title of host publicationSomatic Genome Variation in Animals, Plants, and Microorganisms
Pages45-53
Number of pages9
ISBN (Electronic)9781118647110
DOIs
StatePublished - Jan 1 2016

Bibliographical note

Publisher Copyright:
© 2017 John Wiley & Sons, Inc.

Keywords

  • DNA elimination
  • Programmed genomic changes
  • Somatic cells
  • Vertebrates

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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