Abstract
Introduction: Lifetime exposure to interpersonal violence or abuse has been associated with several chronic diseases, including adult-onset diabetes, yet this pattern has not been confirmed by sex and race within a large cohort. Methods: Data from the Southern Community Cohort Study collected between 2002–2009 and 2012–2015 were used to explore the relationship between lifetime interpersonal violence or abuse and diabetes (N=25,251). Prospective analyses of lower-income people living in the southeastern U.S. were conducted in 2022 to examine the risk of adult-onset diabetes associated with lifetime interpersonal violence or abuse by sex and race. Lifetime interpersonal violence or abuse was defined as (1) physical or psychological violence, threats, or abuse in adulthood (adult interpersonal violence or abuse) and (2) childhood abuse or neglect. Results: After adjustment for potentially confounding factors, adult interpersonal violence or abuse was associated with a 23% increased risk of diabetes (adjusted hazard ratio=1.23; 95% CI=1.16, 1.30). Diabetes risks associated with childhood abuse or neglect were 15% (95% CI=1.02, 1.30) for neglect and 26% (95% CI=1.19, 1.35) for abuse. When combining adult interpersonal violence or abuse and childhood abuse or neglect, the risk of diabetes was 35% higher (adjusted hazard ratio=1.35; 95% CI=1.26, 1.45) than those experiencing no violence, abuse, or neglect. This pattern held among Black and White participants, and among women and men. Conclusions: Both adult interpersonal violence or abuse and childhood abuse or neglect increased the risk of adult-onset diabetes in a dose-dependent pattern for men and women, and by race. Intervention and prevention efforts to reduce adult interpersonal violence or abuse and childhood abuse or neglect could not only reduce the risk of lifetime interpersonal violence or abuse but may also reduce one of the most prevalent chronic diseases, adult-onset diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 783-791 |
| Number of pages | 9 |
| Journal | American Journal of Preventive Medicine |
| Volume | 65 |
| Issue number | 5 |
| DOIs | |
| State | Published - Nov 2023 |
Bibliographical note
Publisher Copyright:© 2023 American Journal of Preventive Medicine
Funding
Research reported in this manuscript was supported by the National Cancer Institute of NIH under Award Number U01CA202979 and by the National Institute on MInorty Health and Health Disparities of the National Institutes of Health under award number U54MD007586 . Southern Community Cohort Study data collection was performed by the Survey and Biospecimen Shared Resource, which is supported in part by the Vanderbilt-Ingram Cancer Center ( P30CA068485 ). MS was partially supported by the National Cancer Institute ( U54CA163069 ). MC was partially supported by the National Center for Advancing Translational Sciences ( KL2TR002245 ). LLB was partially supported by the National Institute of Allergy and Infectious Diseases ( P30AI110527 ) and the National Institute on Minority Health and Health Disparities ( U54MD007586 ). ALC was partially supported by the National Institute on Drug Abuse ( K12DA035150 ).
| Funders | Funder number |
|---|---|
| National Institutes of Health (NIH) | U01CA202979, U54MD007586 |
| Author National Institute on Drug Abuse DA031791 Mark J Ferris National Institute on Drug Abuse DA006634 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA026117 Mark J Ferris National Institute on Alcohol Abuse and Alcoholism AA028162 Elizabeth G Pitts National Institute of General Medical Sciences GM102773 Elizabeth G Pitts Peter McManus Charitable Trust Mark J Ferris National Institute on Drug Abuse | K12DA035150 |
| National Childhood Cancer Registry – National Cancer Institute | |
| National Institute of Allergy and Infectious Diseases | P30AI110527 |
| National Center for Advancing Translational Sciences (NCATS) | KL2TR002245 |
| National Institute on Minority Health and Health Disparities (NIMHD) | |
| Vanderbilt Ingram Cancer Center | P30CA068485, U54CA163069 |
ASJC Scopus subject areas
- Epidemiology
- Public Health, Environmental and Occupational Health