Lipids and the exocytotic machinery of eukaryotic cells

Vytas A. Bankaitis; Andrew J. Morris

doi:10.1016/S0955-0674(03)00076-0

Lipids and the exocytotic machinery of eukaryotic cells

Vytas A. Bankaitis, Andrew J. Morris

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.

Original language	English
Pages (from-to)	389-395
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	15
Issue number	4
DOIs	https://doi.org/10.1016/S0955-0674(03)00076-0
State	Published - Aug 2003

Bibliographical note

Funding Information:
The authors are supported by grants from the National Institutes of Health.

Funding

The authors are supported by grants from the National Institutes of Health.

Funders	Funder number
National Institutes of Health (NIH)

ASJC Scopus subject areas

Cell Biology

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10.1016/S0955-0674(03)00076-0

Cite this

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title = "Lipids and the exocytotic machinery of eukaryotic cells",

abstract = "The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.",

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N2 - The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.

AB - The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.

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U2 - 10.1016/S0955-0674(03)00076-0

DO - 10.1016/S0955-0674(03)00076-0

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Lipids and the exocytotic machinery of eukaryotic cells

Abstract

Bibliographical note

Funding

ASJC Scopus subject areas

Access to Document

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