Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease

Medicine and Dentistry

• Age 20%
• Alzheimer's Disease 100%
• Amyloid 20%
• Amyloid Precursor Protein 20%
• Cyclin-Dependent Kinase 5 100%
• Hyperphosphorylation 40%
• Inflammation 40%
• Inflammatory Disorder 20%
• Lipopolysaccharide 60%
• Lipopolysaccharide-Induced Inflammation 100%
• Microglia 40%
• Neuropathology 20%
• Pathogenesis 20%
• Pathology 100%
• Peptide 20%
• Phosphorylation 20%
• Plaque 40%
• Protein Processing 20%
• Tau 100%

Neuroscience

• Amyloid 20%
• Amyloid Precursor Protein 20%
• Brain 20%
• Cyclin Dependent Kinase 5 100%
• Hippocampus 20%
• Hyperphosphorylation 40%
• Lipopolysaccharide 100%
• Microglia 40%
• Peptide 20%
• Phosphorylation 20%
• Posttranslational Modification 20%
• Seliciclib 20%