Live cell surface labeling with fluorescent ag nanocluster conjugates

Junhua Yu, Sungmoon Choi, Chris I. Richards, Yasuko Antoku, Robert M. Dickson

Research output: Contribution to journalReview articlepeer-review

162 Scopus citations

Abstract

DNA-encapsulated silver clusters are readily conjugated to proteins and serve as alternatives to organic dyes and semiconductor quantum dots. Stable and bright on the bulk and single molecule levels, Ag nanocluster fluorescence is readily observed when staining live cell surfaces. Being significantly brighter and more photostable than organics and much smaller than quantum dots with a single point of attachment, these nanomaterials offer promising new approaches for bulk and single molecule biolabeling.

Original languageEnglish
Pages (from-to)1435-1439
Number of pages5
JournalPhotochemistry and Photobiology
Volume84
Issue number6
DOIs
StatePublished - Nov 2008

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry

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